Motivated by the polygenicity and pleiotropy of genetic associations in complex traits, we developed a method called Decomposition of Genetic Associations (DeGAs) that operates on a series of genome-wide summary statistics across multiple phenotypes. Please check our publication for more information. Yosuke also summarized highlights of the study here.
Y.T. developed the DeGAs web application. M.A.R supervised computational aspects of the study.
Yosuke explains the DeGAs app and teaches viewers how to interpret scores and plots using examples. The coding variants is used as an example.
We provide the interactive DeGAs app for the three datasets analyzed in the paper:
Additionally, following datasets with different parameters are also available in our DeGAs app:
The name of the datasets corresponds to the following conditions: